Early on, Clooney's only dream was to play professional baseball, but following a failed tryout with the Cincinnati Reds he turned to acting with the help of his father, broadcaster Nick Clooney and his aunt, singer and actress Rosemary Clooney.
Beginning in television commercials, Clooney signed on with Warner Brothers in a series of supporting roles, most notably in The Facts of Life, Roseanne and Sisters. His fame and fortune finally assured with his appearance on ER, Clooney left the cast after four years to pursue a career in film.
Notable movie roles have since included The Perfect Storm with Mark Wahlberg, and the remake of the 1960 "Rat Pack" hit, Ocean's Eleven, and its sequel, Ocean's Twelve, released in late 2004 also starring Brad Pitt and Matt Damon.
In 2005, Clooney produced, written and starred in tv series Good Night, and Good Luck based on the life and career of 50's TV journalist Edward R. Murrow.
He also produced and starred in the political thriller Syriana for which Clooney won for Best Supporting Actor at the 2006 Golden Globe Awards and again at the Academy Awards, where Clooney was also nominated for Best Director and Best Screenplay for Good Night, and Good Luck. Clooney also starred in the 2007 Hollywood hit in the lead role of Michael Clayton, for which he was nominated for best actor.